Pharma & biotech
Reproducible LNPs and liposomes, from screening to manufacturing
Encapsulate RNA, proteins, peptides and small molecules in lipid nanoparticles and liposomes with one continuous process, from the first formulation screen to GMP-compatible production
The challenge
What holds formulation back today
- Batch-to-batch variability
- Scale-up forces redevelopment (microfluidic chips must be parallelised)
- Organic solvents to remove and document
- Clogging and downtime
What EncapX® changes
A continuous answer
- The same process at every scale
- Narrow size distribution (±3%) and over 97% encapsulation efficiency
- 35 °C processing for fragile payloads
- No toxic solvents, no residues to remove
Typical actives
Payloads we encapsulate in this market
- mRNA
- siRNA
- antisense RNA
- DNA
- proteins
- antibodies
- peptides
- small molecules
Your development journey
Four stages, one continuous process
01 · Screening
A feasibility study on EncapX® in our lab (size, PDI, encapsulation efficiency, stability).
Feasibility study
02 · Preclinical
Process optimisation and pilot batches for your preclinical work, depending on the project scope and the regulatory context.
Process development
03 · Clinical
Scale-up studies and technology transfer to your GMP site, with a GMP-compatible design.
Scale-up and transfer
04 · Manufacturing
An EncapX® system installed on your site, with training and support.
System on your site
Proof
Evidence for this market
- Compatibility already demonstrated with RNA-based systems (mRNA, siRNA, antisense RNA) and other pharmaceutical actives
- 2023 siRNA paper in Journal of Drug Delivery Science and Technology
- 2024 docetaxel paper (European Meeting on Supercritical Fluids)
- Talk at World Vaccine Congress Europe 2026
- Poster at the LNP Development Summit Europe 2026
Who we work with
Academic labs · Biotechs · Pharma · CDMOs
From first screens to manufacturing partners, the same process stays in place.
FAQ
Questions we hear often
Which payloads can EncapX® encapsulate?
RNA, mRNA, siRNA, antisense RNA, DNA, proteins, antibodies, peptides and small molecules, in liposomes and LNPs.
Can EncapX® be used in a GMP environment?
EncapX® has a GMP-compatible design; qualification in your GMP environment is part of the deployment project.
How does it compare with microfluidics?
It runs continuously, without clogging, and keeps the same process from R&D to production, where microfluidic chips must be multiplied.