Science you can check
Our process builds on the supercritical fluids research of Aix-Marseille University, led by Prof. Elisabeth Badens, Editor-in-Chief of The Journal of Supercritical Fluids. The patented process was invented at Aix-Marseille University by Prof. Elisabeth Badens and Dr Adil Mouahid
A non-exhaustive selection of publications and conferences from our academic partners, on the application areas of our platforms.
Encapsulation
Peer-reviewed work on continuous scCO₂ millifluidics
2023
Supercritical millifluidic process for siRNA encapsulation in nanoliposomes
Martino M., Mouahid A., Sergent M., Desgrouas C., Badens C., Badens E.
Journal of Drug Delivery Science and Technology, 87 (2023), 104804
A continuous scCO₂ millifluidic process producing narrowly distributed nanoliposomes (about 125-150 nm) for siRNA, with effective gene silencing and lower cellular toxicity than commercial transfection agents.
2024
Supercritical millifluidic process for the production of lipid-based formulations of anti-cancer drugs
Mouahid A., Girard C., Badens E.
20th European Meeting on Supercritical Fluids (EMSF), Maribor, Slovenia, May 2024
Pegylated nanoliposomes encapsulating docetaxel, with a millifluidic process that saves fluid, equipment and energy.
Extraction & fractionation
Academic work on supercritical CO₂ extraction and fractionation
2023
Potential of the worldwide-cultivated cyanobacterium Arthrospira platensis for CO₂ mitigation
Gutiérrez Márquez A., Fleury G., Dimitriades-Lemaire A., Alvarez P., Santander G., Crampon C., Badens E., Sassi J-F.
Bioresource Technology Reports, 22, 2023
2022
Valorization of handmade Argan press cake by supercritical CO₂ extraction
Mouahid A., Claeys-Bruno M., Bombarda I., Amat S., Ciavarella A., Myotte E., Nisteron J.P., Crampon C., Badens E.
Food and Bioproducts Processing, 137, 2022
2022
Supercritical CO₂ extraction of oil from Moroccan unroasted Argan kernels
Mouahid A., Bombarda I., Claeys-Bruno M., Amat S., Myotte E., Nisteron J.P., Crampon C., Badens E.
Journal of CO₂ Utilization, 59, 101952, 2022
2021
A new correlation for predicting flooding point in supercritical fractionation packed columns
Pieck A., Crampon C., Aymeric F., Badens E.
The Journal of Supercritical Fluids, 179, 105404, 2021
2021
Supercritical CO₂ extraction of Moroccan Argan (Argania spinosa L.) oil: extraction kinetics and solubility determination
Mouahid A., Bombarda I., Claeys-Bruno M., Amat S., Myotte E., Nisteron J.P., Crampon C., Badens E.
Journal of CO₂ Utilization, 46, 101458, 2021
2020
Supercritical CO₂ extraction of neutral lipids from Nannochloropsis maritima and Nannochloropsis salina
Mouahid A., Seengeon K., Martino M., Crampon C., Kramer A., Badens E.
The Journal of Supercritical Fluids, 165, 2020
2020
Sclareol purification using supercritical fractionation process: a modelling case study
Dufour C., Crampon C., Delbecque C., Garry P-P., Badens E.
The Journal of Supercritical Fluids, 159, 2020
2018
Supercritical CO₂ extraction of oil from Jatropha curcas: an experimental and modelling study
Mouahid A., Bouanga H., Crampon C., Badens E.
The Journal of Supercritical Fluids, 141, 2-11, 2018
Conferences
On stage with the process
2026
Redefining Nanocarrier Manufacturing with Scalable Continuous scCO₂ Processing for Advanced Vaccine Delivery
World Vaccine Congress Europe, Amsterdam · talk, Dr Elissandro Klein
2026
From Formulation to Bioproduction: Why Next-Generation Therapies Require Next-Generation Encapsulation Technologies
BIOPC 2026, Lyon · talk, Fabien Balme
2026
Continuous Production of Lipid-Based Nanoparticles Using Supercritical CO₂
5th Lipid Nanoparticles Development Summit Europe, Berlin · poster
2026
Festival of Biologics
Basel · poster
2026
Continuous supercritical CO₂ fractionation of wet microalgal suspensions for selective recovery of neutral lipids
EMSF 2026, Clausthal-Zellerfeld · talk
Press
Coverage of the platform
2026
Biotech One révolutionne l'encapsulation des substances actives
Le Journal des Entreprises, June 2026
2026
Le Journal des Entreprises
April 2026, on the €1M round
2026
CFNEWS
April 2026